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generation deep sequencing genomic dna  (Thermo Fisher)


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    Thermo Fisher generation deep sequencing genomic dna
    Generation Deep Sequencing Genomic Dna, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/generation deep sequencing genomic dna/product/Thermo Fisher
    Average 99 stars, based on 1 article reviews
    generation deep sequencing genomic dna - by Bioz Stars, 2026-06
    99/100 stars

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    generation deep sequencing genomic dna  (Thermo Fisher)
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    Thermo Fisher generation deep sequencing genomic dna
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    next-generation deep sequencing of the genomic dna of cd19+/cd5+/cd23- (b1a) splenocytes  (Adaptive Biotechnologies Corp)
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    Adaptive Biotechnologies Corp next-generation deep sequencing of the genomic dna of cd19+/cd5+/cd23- (b1a) splenocytes
    SOX11 expression leads to clonal expansion of B cells. (A) <t>Deep</t> <t>sequencing</t> of the genomic <t>DNA</t> from B1a cells showing increased IgH gene clonality in Tg-SOX11 mice vs WT mice. (B) Decreased total productive rearrangements in the BCR repertoire of B1a cells of Tg-SOX11 mice vs WT mice showing a decrease in IgH gene diversity. (C) Frequency of the top 10 rearrangements compared with all other rearrangements of the IgH locus in B1a cells showing clonality in 2 Tg-SOX11 mice and oligoclonality in 2 Tg-SOX11 mice vs normal IgH diversity in the 2 WT mice. (D) Productive frequency of the top 100 IgH gene rearrangements shows loss of IgH diversity in all Tg-SOX11 mice (N = 4) as compared with WT mice (N = 2). In the histogram, each color represents a unique IgH clone, whereas the numerals represent the frequency of top clone in each mouse.
    Next Generation Deep Sequencing Of The Genomic Dna Of Cd19+/Cd5+/Cd23 (B1a) Splenocytes, supplied by Adaptive Biotechnologies Corp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    SOX11 expression leads to clonal expansion of B cells. (A) Deep sequencing of the genomic DNA from B1a cells showing increased IgH gene clonality in Tg-SOX11 mice vs WT mice. (B) Decreased total productive rearrangements in the BCR repertoire of B1a cells of Tg-SOX11 mice vs WT mice showing a decrease in IgH gene diversity. (C) Frequency of the top 10 rearrangements compared with all other rearrangements of the IgH locus in B1a cells showing clonality in 2 Tg-SOX11 mice and oligoclonality in 2 Tg-SOX11 mice vs normal IgH diversity in the 2 WT mice. (D) Productive frequency of the top 100 IgH gene rearrangements shows loss of IgH diversity in all Tg-SOX11 mice (N = 4) as compared with WT mice (N = 2). In the histogram, each color represents a unique IgH clone, whereas the numerals represent the frequency of top clone in each mouse.

    Journal: Blood

    Article Title: SOX11 augments BCR signaling to drive MCL-like tumor development

    doi: 10.1182/blood-2018-02-832535

    Figure Lengend Snippet: SOX11 expression leads to clonal expansion of B cells. (A) Deep sequencing of the genomic DNA from B1a cells showing increased IgH gene clonality in Tg-SOX11 mice vs WT mice. (B) Decreased total productive rearrangements in the BCR repertoire of B1a cells of Tg-SOX11 mice vs WT mice showing a decrease in IgH gene diversity. (C) Frequency of the top 10 rearrangements compared with all other rearrangements of the IgH locus in B1a cells showing clonality in 2 Tg-SOX11 mice and oligoclonality in 2 Tg-SOX11 mice vs normal IgH diversity in the 2 WT mice. (D) Productive frequency of the top 100 IgH gene rearrangements shows loss of IgH diversity in all Tg-SOX11 mice (N = 4) as compared with WT mice (N = 2). In the histogram, each color represents a unique IgH clone, whereas the numerals represent the frequency of top clone in each mouse.

    Article Snippet: We conducted next-generation deep sequencing of the genomic DNA of CD19 + /CD5 + /CD23 − (B1a) splenocytes to study their IgH gene repertoire (Adaptive Biotechnologies).

    Techniques: Expressing, Sequencing